Drosophila melanogaster as an indispensable model to decipher the mode of action of neurotoxic compounds

نویسندگان

چکیده

Exposure to some toxic compounds causes structural and behavioral anomalies associated with the neurons in later stage of life. Those are termed as a neurotoxicant, which can be physical factor, toxin, an infection, radiation, or maybe drug. The incongruities caused due neurotoxicant further depend on toxicity compound. More importantly, neurotoxicity compound is concentration time point exposure. neurodevelopmental defect appears depending A may delay developmental time, defective growth, abnormality many organs, including sensory abnormalities, death fetus stage. Numerous model organisms employed assess effect neurotoxicants. current review summarizes several methods used check their using organism Drosophila melanogaster.

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ژورنال

عنوان ژورنال: Biocell

سال: 2023

ISSN: ['0327-9545', '1667-5746']

DOI: https://doi.org/10.32604/biocell.2022.023392